Description

Ponstan Suspension contains mefenamic acid, a nonsteroidal anti-inflammatory medicine used for short-term relief of mild to moderate pain and inflammation. It is supplied as an oral suspension for easier administration, particularly when swallowing tablets is difficult.

• Manufacturer Name: LCI Pakistan
• Drug Class: Nonsteroidal anti-inflammatory drug (NSAID)
• Dosage Form: Oral suspension
• Storage: Store at room temperature, protected from heat, light and moisture. Keep the bottle tightly closed and out of reach of children. Shake well before each use.
• Pack Size: Pack of 1 Suspension

Ingredients

• Active ingredient: Mefenamic acid 50mg per 5ml
• Inactive ingredients: Pharmaceutical excipients as listed on the product label

Benefits

• Short-term relief of mild to moderate pain
• Relief of pain associated with inflammation
• Menstrual pain and cramps
• Musculoskeletal, dental or other acute painful conditions when prescribed

Usage & Safety

For Adult

• Use only as directed by a doctor or pharmacist.
• A commonly used adult regimen is 500mg initially, followed by 250mg every 6 hours as needed.
• With this 50mg/5ml suspension, 500mg equals 50ml and 250mg equals 25ml.
• Use the lowest effective dose for the shortest possible duration, preferably with or after food.
• Do not use continuously for longer than prescribed, and do not combine with another NSAID.

For Children

• Use in children only on the advice of a healthcare professional.
• A commonly used pediatric regimen is approximately 25mg/kg/day divided into 3 doses, based on body weight and clinical need.
• Do not exceed the prescribed dose or duration; treatment is generally limited to short-term use.
• Not recommended for infants younger than 6 months unless specifically prescribed by a pediatrician.
• Measure each dose with an oral syringe or calibrated measuring device and shake the suspension well before use.

Side Effects

• Common effects may include nausea, vomiting, indigestion, stomach pain, diarrhea, constipation, dizziness or headache.
• Stop use and seek medical help for black stools, vomiting blood, severe abdominal pain or persistent diarrhea.
• Seek urgent care for facial swelling, breathing difficulty, severe rash, blistering or skin peeling.
• Serious effects can include stomach or intestinal bleeding, kidney injury, liver problems, fluid retention, worsening heart failure, heart attack or stroke.
• Overdose may cause marked drowsiness, vomiting, abdominal pain, confusion, seizures or other nervous-system effects.

Contraindications

• Do not use in people with allergy to mefenamic acid, aspirin or other NSAIDs.
• Avoid in patients with a history of NSAID-related asthma, wheezing, hives or severe allergic reactions.
• Contraindicated in active stomach or intestinal ulcer, gastrointestinal bleeding or inflammatory bowel disease unless specifically directed by a specialist.
• Avoid in severe kidney, liver or heart disease and in patients with uncontrolled high blood pressure unless medically supervised.
• Do not use around or after coronary artery bypass surgery.
• Do not use together with other NSAIDs, including ibuprofen, naproxen, diclofenac or high-dose aspirin, unless prescribed.

Precautions & Warnings

• Do not combine with other NSAIDs or aspirin unless directed by a healthcare professional.
• May increase bleeding risk with warfarin, apixaban, rivaroxaban, dabigatran, clopidogrel and other anticoagulant or antiplatelet medicines.
• May reduce the effect of some blood-pressure medicines and increase kidney risk with ACE inhibitors, ARBs or diuretics.
• Use caution with corticosteroids, SSRIs, lithium, methotrexate, cyclosporine, tacrolimus and other medicines that can affect the kidneys or stomach.
• Alcohol may increase stomach irritation and bleeding risk; avoid or limit it.
• Take with food or milk if stomach upset occurs, but do not use food to prevent serious NSAID complications.

Pregnancy

• Ask a doctor before use during pregnancy.
• Avoid during the third trimester because NSAIDs may harm the fetus and affect labor, fetal circulation or kidney function.
• Use during the first or second trimester only if clearly needed and prescribed by a healthcare professional.
• Discuss breastfeeding with a doctor before use; short-term treatment may require individualized assessment.