{"product_id":"combiviar-40mcg-6mcg-rotacaps-40s","title":"Combiviar 40mcg\/6mcg Rotacaps (40s)","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\u003cp\u003eCombiviar is an inhaled combination medicine containing budesonide and formoterol for maintenance treatment of asthma and chronic obstructive pulmonary disease. Each rotacap is intended for inhalation through a compatible dry-powder inhaler and should not be swallowed.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eManufacturer Name: Highnoon\u003c\/li\u003e\n\u003cli\u003eDrug Class: Inhaled corticosteroid and long-acting beta2-adrenergic agonist combination\u003c\/li\u003e\n\u003cli\u003eDosage Form: Dry-Powder Inhalation Capsule (Rotacap)\u003c\/li\u003e\n\u003cli\u003eStorage: Store below 25°C in a dry place, protected from moisture, heat, and direct sunlight. Keep the capsules in the original packaging until use and keep out of reach of children.\u003c\/li\u003e\n\u003cli\u003ePack Size: Pack of 40 Capsules\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eIngredients\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003eBudesonide 400 mcg\u003c\/li\u003e\n\u003cli\u003eFormoterol fumarate equivalent to formoterol 6 mcg\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eBenefits\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003eMaintenance treatment of asthma when inhaled corticosteroid and long-acting bronchodilator therapy are appropriate.\u003c\/li\u003e\n\u003cli\u003eMaintenance treatment of chronic obstructive pulmonary disease with persistent airflow limitation and recurrent symptoms.\u003c\/li\u003e\n\u003cli\u003eHelps reduce airway inflammation, wheezing, breathlessness, and bronchoconstriction.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eUsage \u0026amp; Safety\u003c\/h3\u003e\u003ch4\u003eFor Adult\u003c\/h4\u003e\u003cul\u003e\n\u003cli\u003eUse only by oral inhalation with the prescribed compatible rotacap inhaler; do not swallow the capsule.\u003c\/li\u003e\n\u003cli\u003eA commonly prescribed adult regimen is one rotacap inhaled twice daily, but the exact dose and frequency must be individualized by the prescriber.\u003c\/li\u003e\n\u003cli\u003eLoad the capsule into the inhaler immediately before use, pierce it according to the device instructions, and inhale the powder deeply through the mouth.\u003c\/li\u003e\n\u003cli\u003eRinse the mouth with water and spit it out after each dose to reduce the risk of oral thrush and hoarseness.\u003c\/li\u003e\n\u003cli\u003eThis product is not intended to provide immediate relief during a sudden severe asthma attack; use the prescribed rescue inhaler for acute symptoms.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch4\u003eFor Children\u003c\/h4\u003e\u003cul\u003e\n\u003cli\u003ePediatric use should be determined by a physician based on age, diagnosis, symptom severity, and ability to use the inhaler correctly.\u003c\/li\u003e\n\u003cli\u003eSafety and effectiveness of this specific 400 mcg\/6 mcg rotacap strength are not established for young children.\u003c\/li\u003e\n\u003cli\u003eChildren should use the product only under adult supervision and should not swallow the capsule.\u003c\/li\u003e\n\u003cli\u003eNo weight-based dosing recommendation is established; do not adjust the dose according to body weight without medical advice.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch4\u003eSide Effects\u003c\/h4\u003e\u003cul\u003e\n\u003cli\u003eCommon effects may include throat irritation, hoarseness, cough, headache, tremor, nervousness, muscle cramps, nausea, and palpitations.\u003c\/li\u003e\n\u003cli\u003eOral candidiasis may occur; rinsing and spitting after inhalation can help reduce this risk.\u003c\/li\u003e\n\u003cli\u003eFormoterol may cause fast heartbeat, blood-pressure changes, or low potassium, particularly with excessive use or in susceptible patients.\u003c\/li\u003e\n\u003cli\u003eSerious effects may include paradoxical bronchospasm, significant arrhythmia, severe allergic reaction, adrenal suppression, vision changes, or pneumonia.\u003c\/li\u003e\n\u003cli\u003eReport persistent white patches in the mouth, worsening wheezing, severe weakness, irregular heartbeat, or signs of infection.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch4\u003eContraindications\u003c\/h4\u003e\u003cul\u003e\n\u003cli\u003eDo not use in patients with known allergy to budesonide, formoterol, lactose or any other component.\u003c\/li\u003e\n\u003cli\u003eDo not use as the sole treatment for acute bronchospasm or status asthmaticus.\u003c\/li\u003e\n\u003cli\u003eUse cautiously in patients with heart disease, arrhythmias, hypertension, hyperthyroidism, diabetes, seizure disorders, osteoporosis, glaucoma, cataracts, or untreated respiratory infections.\u003c\/li\u003e\n\u003cli\u003eInhaled corticosteroids may increase the risk of oral fungal infections, pneumonia, adrenal suppression, reduced bone mineral density, and growth effects with prolonged or high-dose use.\u003c\/li\u003e\n\u003cli\u003eSeek urgent medical care for worsening breathing, rapidly increasing rescue-inhaler use, chest pain, severe palpitations, facial swelling, or difficulty breathing immediately after inhalation.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch4\u003ePrecautions \u0026amp; Warnings\u003c\/h4\u003e\u003cul\u003e\n\u003cli\u003eOther long-acting beta2 agonists or excessive use of short-acting beta2 agonists may increase cardiovascular and low-potassium effects.\u003c\/li\u003e\n\u003cli\u003eBeta-blockers, including some eye drops, may reduce the bronchodilator effect and can cause bronchospasm.\u003c\/li\u003e\n\u003cli\u003eStrong CYP3A4 inhibitors such as ketoconazole, itraconazole, clarithromycin, ritonavir, and cobicistat may increase budesonide exposure and corticosteroid-related effects.\u003c\/li\u003e\n\u003cli\u003eDiuretics, corticosteroids, methylxanthines, and some medicines that prolong the QT interval may increase the risk of low potassium or cardiac effects.\u003c\/li\u003e\n\u003cli\u003eMonoamine oxidase inhibitors and tricyclic antidepressants may enhance cardiovascular effects; inform the prescriber before use.\u003c\/li\u003e\n\u003cli\u003eThere are no important routine food restrictions, but grapefruit products should be discussed with a healthcare professional when strong CYP3A4-inhibiting medicines are being used.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003ePregnancy\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003eUse during pregnancy only when clearly needed and under medical supervision; uncontrolled asthma can also pose risks to the mother and fetus.\u003c\/li\u003e\n\u003cli\u003eAvailable evidence for inhaled budesonide is generally reassuring, but the combination should be continued, started, or changed only on professional advice.\u003c\/li\u003e\n\u003cli\u003eTell the prescriber if pregnancy is planned or confirmed; use the lowest effective dose that maintains control.\u003c\/li\u003e\n\u003cli\u003eIt is not known whether clinically significant amounts pass into breast milk. Consult a healthcare professional before breastfeeding use.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Highnoon Laboratories","offers":[{"title":"Default Title","offer_id":50532081401971,"sku":"377446","price":729.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0675\/9910\/6163\/files\/Combiviar_tab_400_6mcg_40s.png?v=1790367080","url":"https:\/\/alrehmanpharmacy.com\/products\/combiviar-40mcg-6mcg-rotacaps-40s","provider":"Al-Rehman Pharmacy \u0026 Cosmetics","version":"1.0","type":"link"}