{"product_id":"centaurus-0-5mg-tablets-30s","title":"Centaurus 0.5mg Tablets (30s)","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\u003cp\u003eCentaurus 0.5 mg Tablets contain entecavir, an antiviral medicine used to suppress hepatitis B virus replication. It is a prescription medicine intended for use under specialist medical supervision.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eManufacturer Name: Ferozsons\u003c\/li\u003e\n\u003cli\u003eDrug Class: Nucleoside analogue antiviral\u003c\/li\u003e\n\u003cli\u003eDosage Form: Immediate-Release Tablet\u003c\/li\u003e\n\u003cli\u003eStorage: Store at controlled room temperature, generally 20°C to 25°C. Protect from moisture and keep out of reach of children.\u003c\/li\u003e\n\u003cli\u003ePack Size: Pack of 30 Tablets\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eIngredients\u003c\/h3\u003e\u003cul\u003e\u003cli\u003eEntecavir 0.5 mg\u003c\/li\u003e\u003c\/ul\u003e\u003ch3\u003eBenefits\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003eTreatment of chronic hepatitis B virus infection in adults with evidence of active viral replication.\u003c\/li\u003e\n\u003cli\u003eMay help reduce hepatitis B viral load and improve liver inflammation and liver-function markers.\u003c\/li\u003e\n\u003cli\u003eUse is determined by the prescriber based on viral load, liver status, resistance history, and kidney function.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eUsage \u0026amp; Safety\u003c\/h3\u003e\u003ch4\u003eFor Adult\u003c\/h4\u003e\u003cul\u003e\n\u003cli\u003eUsual adult dose for previously untreated chronic hepatitis B with compensated liver disease: 0.5 mg orally once daily.\u003c\/li\u003e\n\u003cli\u003eFor lamivudine-resistant infection or decompensated liver disease, the usual prescribed dose may be 1 mg once daily; specialist supervision is required.\u003c\/li\u003e\n\u003cli\u003eTake on an empty stomach, at least 2 hours after a meal and at least 2 hours before the next meal.\u003c\/li\u003e\n\u003cli\u003eDosage reduction is required in patients with reduced kidney function; follow the prescriber's instructions.\u003c\/li\u003e\n\u003cli\u003eDo not stop treatment without medical advice because hepatitis B may worsen after discontinuation.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch4\u003eFor Children\u003c\/h4\u003e\u003cul\u003e\n\u003cli\u003eMay be used in children and adolescents at least 2 years old and weighing at least 10 kg when prescribed by a specialist.\u003c\/li\u003e\n\u003cli\u003ePediatric dosing is weight-based and may range from 0.15 mg to 0.5 mg once daily for treatment-naive patients; the maximum dose is generally 0.5 mg daily.\u003c\/li\u003e\n\u003cli\u003eChildren with lamivudine-resistant infection may require specialist-adjusted dosing up to 1 mg daily.\u003c\/li\u003e\n\u003cli\u003eSafety and effectiveness have not been established for children younger than 2 years or weighing less than 10 kg.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch4\u003eSide Effects\u003c\/h4\u003e\u003cul\u003e\n\u003cli\u003eCommon effects may include headache, tiredness, dizziness, nausea, abdominal discomfort, and indigestion.\u003c\/li\u003e\n\u003cli\u003eAbnormal liver-function tests or increased liver enzymes may occur.\u003c\/li\u003e\n\u003cli\u003eSeek urgent medical help for severe weakness, persistent vomiting, abdominal pain, rapid breathing, breathing difficulty, unusual muscle pain, yellowing of the skin or eyes, or marked swelling of the abdomen.\u003c\/li\u003e\n\u003cli\u003eSerious but uncommon reactions include lactic acidosis, hepatomegaly with steatosis, severe hepatitis flare, and allergic reactions.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch4\u003eContraindications\u003c\/h4\u003e\u003cul\u003e\n\u003cli\u003eDo not use in patients with a known allergy to entecavir or any tablet ingredient.\u003c\/li\u003e\n\u003cli\u003eUse cautiously in patients with kidney impairment, liver decompensation, or a history of treatment with nucleoside or nucleotide antivirals.\u003c\/li\u003e\n\u003cli\u003ePatients should be tested for HIV before treatment when clinically appropriate; entecavir should not be used as the sole treatment for HIV infection.\u003c\/li\u003e\n\u003cli\u003eMonitor for lactic acidosis and severe liver enlargement with fatty liver, particularly in patients with liver disease or other risk factors.\u003c\/li\u003e\n\u003cli\u003eStopping treatment can cause a serious flare or worsening of hepatitis B and requires medical monitoring.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch4\u003ePrecautions \u0026amp; Warnings\u003c\/h4\u003e\u003cul\u003e\n\u003cli\u003eMedicines that reduce kidney function or compete for renal tubular secretion may increase entecavir or co-administered medicine levels.\u003c\/li\u003e\n\u003cli\u003eTell the prescriber about nephrotoxic medicines, including certain antivirals, antibiotics, chemotherapy medicines, and other drugs that may affect kidney function.\u003c\/li\u003e\n\u003cli\u003eUse with lamivudine, emtricitabine, or other medicines active against hepatitis B or HIV requires specialist review to avoid ineffective or duplicate therapy.\u003c\/li\u003e\n\u003cli\u003eFood reduces absorption when taken with a meal; take the tablet on an empty stomach as directed.\u003c\/li\u003e\n\u003cli\u003eEntecavir has limited metabolism through liver enzyme pathways, but all prescription, non-prescription, and herbal medicines should still be disclosed.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003ePregnancy\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003eHuman pregnancy data are limited; use during pregnancy only when specifically recommended by a physician after considering benefits and risks.\u003c\/li\u003e\n\u003cli\u003ePatients who are pregnant or planning pregnancy should discuss hepatitis B treatment options with a specialist; an alternative antiviral may be preferred in some situations.\u003c\/li\u003e\n\u003cli\u003eEntecavir has not been adequately studied in breastfeeding mothers, and an alternative may be preferred, especially when nursing a newborn or premature infant.\u003c\/li\u003e\n\u003cli\u003eBreastfeeding decisions should consider the mother's need for treatment and prevention of hepatitis B transmission; the infant should receive hepatitis B vaccine and immune globulin at birth when indicated.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Ferozsons Laboratories","offers":[{"title":"Default Title","offer_id":48397223493747,"sku":"78607","price":3622.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0675\/9910\/6163\/files\/Centaurus_0_5mg_Tablets.png?v=1790095746","url":"https:\/\/alrehmanpharmacy.com\/products\/centaurus-0-5mg-tablets-30s","provider":"Al-Rehman Pharmacy \u0026 Cosmetics","version":"1.0","type":"link"}