{"product_id":"amaryl-m-sr-2mg-500mg-tablets-30s","title":"Amaryl M SR 2mg\/500mg Tablets (30s)","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\u003cp\u003eAmaryl MSR is a fixed-dose oral antidiabetic combination containing glimepiride and sustained-release metformin. It is used with diet and exercise to improve blood glucose control in adults with type 2 diabetes mellitus.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eManufacturer Name: Sanofi\u003c\/li\u003e\n\u003cli\u003eDrug Class: Sulfonylurea and biguanide antihyperglycemic combination\u003c\/li\u003e\n\u003cli\u003eDosage Form: Sustained-Release Tablet\u003c\/li\u003e\n\u003cli\u003eStorage: Store at room temperature below 30°C in a dry place, protected from heat, moisture, and direct sunlight. Keep out of reach of children.\u003c\/li\u003e\n\u003cli\u003ePack Size: Pack of 30 Tablets\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eIngredients\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003eGlimepiride 2 mg\u003c\/li\u003e\n\u003cli\u003eMetformin hydrochloride 500 mg, sustained-release\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eBenefits\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003eUsed as an adjunct to diet and exercise for type 2 diabetes mellitus.\u003c\/li\u003e\n\u003cli\u003eHelps improve fasting and post-meal blood glucose control when treatment with a single medicine is insufficient.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eUsage \u0026amp; Safety\u003c\/h3\u003e\u003ch4\u003eFor Adult\u003c\/h4\u003e\u003cul\u003e\n\u003cli\u003eTake strictly as prescribed by the physician, usually once daily with or immediately after the main meal.\u003c\/li\u003e\n\u003cli\u003eSwallow the tablet whole with water; do not crush, chew, or split the sustained-release tablet.\u003c\/li\u003e\n\u003cli\u003eDose adjustments should be based on blood glucose response, kidney function, tolerability, and previous antidiabetic therapy.\u003c\/li\u003e\n\u003cli\u003eRegular monitoring of blood glucose and glycated hemoglobin is recommended.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch4\u003eFor Children\u003c\/h4\u003e\u003cul\u003e\n\u003cli\u003eSafety and effectiveness in children and adolescents have not been adequately established.\u003c\/li\u003e\n\u003cli\u003eNot routinely recommended for patients under 18 years unless specifically prescribed by a specialist.\u003c\/li\u003e\n\u003cli\u003eNo established pediatric weight-based dose or weight limit is available for this fixed-strength combination.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch4\u003eSide Effects\u003c\/h4\u003e\u003cul\u003e\n\u003cli\u003eCommon effects may include nausea, diarrhea, abdominal discomfort, loss of appetite, vomiting, and metallic taste.\u003c\/li\u003e\n\u003cli\u003eLow blood sugar may cause sweating, tremor, hunger, dizziness, weakness, confusion, palpitations, or blurred vision.\u003c\/li\u003e\n\u003cli\u003eOther possible effects include headache, weight gain, skin rash, and changes in taste.\u003c\/li\u003e\n\u003cli\u003eSeek urgent medical attention for severe or persistent hypoglycemia, breathing difficulty, extreme weakness, muscle pain, unusual sleepiness, or signs of lactic acidosis.\u003c\/li\u003e\n\u003cli\u003eRare but serious reactions include severe allergic skin reactions, liver injury, blood-cell disorders, and vitamin B12 deficiency with long-term metformin use.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch4\u003eContraindications\u003c\/h4\u003e\u003cul\u003e\n\u003cli\u003eDo not use in patients with type 1 diabetes, diabetic ketoacidosis, diabetic coma, or severe uncontrolled diabetes requiring insulin.\u003c\/li\u003e\n\u003cli\u003eContraindicated in severe kidney impairment or acute conditions that may reduce kidney function.\u003c\/li\u003e\n\u003cli\u003eDo not use in severe liver disease, severe heart or respiratory failure, shock, or conditions associated with tissue hypoxia.\u003c\/li\u003e\n\u003cli\u003eAvoid in patients with a known allergy to glimepiride, metformin, sulfonylureas, sulfonamides, or any tablet ingredient.\u003c\/li\u003e\n\u003cli\u003eTemporarily discontinue around certain iodinated contrast-imaging procedures when advised by a healthcare professional.\u003c\/li\u003e\n\u003cli\u003eUse cautiously in older adults, patients with irregular meals, adrenal or pituitary disorders, or those at increased risk of hypoglycemia.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch4\u003ePrecautions \u0026amp; Warnings\u003c\/h4\u003e\u003cul\u003e\n\u003cli\u003eOther antidiabetic medicines and insulin may increase the risk of hypoglycemia.\u003c\/li\u003e\n\u003cli\u003eAlcohol may increase the risk of hypoglycemia and lactic acidosis and should be avoided or strictly limited.\u003c\/li\u003e\n\u003cli\u003eMedicines such as beta-blockers, ACE inhibitors, salicylates, some NSAIDs, fluconazole, and other glucose-lowering drugs may enhance the glucose-lowering effect.\u003c\/li\u003e\n\u003cli\u003eCorticosteroids, thiazide diuretics, sympathomimetics, thyroid medicines, and some hormonal medicines may reduce glucose control.\u003c\/li\u003e\n\u003cli\u003eCimetidine, rifampicin, anticoagulants, and other medicines affecting glimepiride metabolism may alter its effect.\u003c\/li\u003e\n\u003cli\u003eTell the doctor about all medicines and supplements, especially before contrast imaging or treatment with medicines that can affect kidney function.\u003c\/li\u003e\n\u003cli\u003eTake with food as directed and avoid skipping meals while using this medicine.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003ePregnancy\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003eDo not use during pregnancy unless specifically prescribed by a specialist; insulin is generally preferred for blood-glucose control during pregnancy.\u003c\/li\u003e\n\u003cli\u003eContact the healthcare provider promptly if pregnancy occurs or is planned.\u003c\/li\u003e\n\u003cli\u003eBreastfeeding is generally not recommended during treatment unless the physician determines that an alternative is unsuitable.\u003c\/li\u003e\n\u003cli\u003eInfants exposed through breast milk may require monitoring for low blood sugar.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Sanofi","offers":[{"title":"Default Title","offer_id":50532031037555,"sku":"95703","price":1170.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0675\/9910\/6163\/files\/Amaryl_Msr_2mg_500mg_Tablets.png?v=1790366331","url":"https:\/\/alrehmanpharmacy.com\/products\/amaryl-m-sr-2mg-500mg-tablets-30s","provider":"Al-Rehman Pharmacy \u0026 Cosmetics","version":"1.0","type":"link"}